Science & Chill

Episode 38: Free Radical Biology & the Past & Present of Respiratory Physiology with Dr. Thomas Clanton

October 21, 2021

My guest today is Dr. Thomas Clanton. Dr. Clanton is a professor in applied physiology and kinesiology at the University of Florida, where he conducts research on immune cells in skeletal and cardiac muscle biology, the origins of heat stroke, and the effects of heat stroke on physiology and epigenetic regulation. Dr. Clanton is also a member of my PhD advisory committee and has been highly influential on the way I think about and do science throughout my graduate school career.

We begin our conversation with a deep and lengthy dive into Dr. Clanton’s scientific career — why he got into science, his early career work in respiratory and lung physiology, and what led him to become a cell biologist who now primarily focuses on animal models. We cover some basics of respiratory physiology and also talk about inspiratory muscle training devices — one for which Dr. Clanton actually has held a patent on for the last 40 or so years.

We then talk about free radical biology, reactive oxygen species in normal function and health and disease, and the key role of free radicals as signaling molecules throughout the body.

I was so glad to sit down with Dr. Clanton for our brief chat, and know that you will thoroughly enjoy this tour through what is a pretty jam-packed scientific career. 



UF Muscle Stress Physiology Lab:

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